AANS Neurosurgeon | Volume 29, Number 2, 2020


Stem Cell-Derived Neurons Stop Seizures and Improve Cognitive Function

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People with untreatable epilepsy may one day have a treatment: ‘convincing’ their own cells to become the neurons they need

About 3.4 million Americans, or 1.2 percent of the population, have active epilepsy. Although the majority respond to medication, between 20 and 40 percent of patients with epilepsy continue to have seizures even after trying multiple anti-seizure drugs. Even when the drugs do work, people may develop cognitive and memory problems and depression, likely from the combination of the underlying seizure disorder and the drugs to treat it.

A team led by Ashok K. Shetty, PhD, a professor in the Department of Molecular and Cellular Medicine at the Texas A&M College of Medicine, associate director of the Institute for Regenerative Medicine and a research career scientist at the Olin E. Teague Veterans’ Medical Center, part of the Central Texas Veterans Health Care System, is working on a better and permanent treatment for epilepsy. 

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olory-togbe regis | January 27, 2019 at 6:04 pm

Temporal lobectomy associated to amygdalo-hypocampectomy shows satisfaying results in control of temporal epylepsy.
A team of brussels neurosurgery departement use a surgical approach basing in cutting connection ways of seizure transmission in temporal epilepsy.
But this experience of Professor Ashok is interesting and more evidence with an large population like multicentric experience is needed and should be interesting to confirm this very wonderfull research