Rare Neurological Disorder Documented Following COVID-19 Vaccination

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Clinicians in India and England report cases Guillain-Barré syndrome after individuals received COVID-19 vaccines

In two separate articles, clinicians in India and England report cases of a rare neurological disorder called Guillain-Barré syndrome after individuals were vaccinated against COVID-19.

Both reports describe an unusual variant of Guillain-Barré syndrome characterized by prominent facial weakness. Seven cases were reported from a regional medical center in Kerala, India, where approximately 1.2 million people were vaccinated with the AstraZeneca COVID-19 vaccine. Four cases were reported from Nottingham, England, in an area in which approximately 700,000 people received the same vaccine. All 11 cases were among people who had received that vaccine 10–22 days earlier.

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The frequency of Guillain-Barré syndrome in these areas was estimated to be up to 10 times greater than expected.

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