Neuroscientists Focus on Cell Mechanism That Promotes Chronic Pain
Researchers have discovered a new pain-signaling pathway in nerve cells that eventually could make a good target for new drugs to fight chronic pain.
The findings, published by a UT Dallas neuroscientist and his colleagues, suggest that inhibiting a process called phosphorylation occurring outside of nerve cells might disrupt pain signals, and provide an alternative to opioid drugs for alleviating chronic pain.
Dr. Ted Price, the study’s co-author and associate professor of neuroscience in the School of Behavioral and Brain Sciences at UT Dallas, said the finding is significant.
“We found a key new signaling pathway that can be managed,” Price said. “Now we hope we can use the findings to discover a new drug.”
Phosphorylation is a biological process that occurs when a kinase — a type of enzyme — attaches a chemical called phosphate to a protein. This common process modifies proteins and their functions.
Click here to read more.
Kranzler Chicago Review Course in Neurosurgery
Jan. 24-31, 2020; Chicago
46th Annual Richard Lende Winter Neurosurgery Conference
Jan. 31-Feb. 3, 2020; Snowbird, Utah
Third Annual Cedars Sinai Intracranial Hypotension Symposium
Feb. 8, 2020; Los Angeles
2020 Managing Coding and Reimbursement Challenges
Feb. 14-16, 2020; Las Vegas
13th Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery
Feb. 21-23, 2020; Lake Buena Vista, Fla.