Focal cortical dysplasia is a type of medication-resistant epilepsy. Since the cause is unknown, treatment options are limited to invasive brain surgery which may be ineffective. Now, UC San Diego School of Medicine researchers have developed a new human brain organoid model to study the mechanisms of this disease. The model helps the team uncover the involvement of RHOA — a gene that regulates cell-cell adhesion proteins — in neuronal proliferation.
AANS Neurosurgeon is the official socioeconomic publication of the American Association of Neurological Surgeons (AANS) and features information and analysis for contemporary neurosurgical practice. Published monthly online, AANS Neurosurgeon focuses on issues related to neurosurgery legislation, the workforce and practice management.
