AANS Neurosurgeon | Volume 26, Number 1, 2017


TSRI Study Identifies New Type of Protein Clump that May Be Implicated in ALS

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The Findings May Lead to New Therapies for ALS and Other Neurodegenerative Conditions 

“We have uncovered a new molecular mechanism underlying neurodegeneration,” said Claudio Joazeiro, associate professor of cell and molecular biology at The Scripps Research Institute (TSRI) and senior author of the new study. “This could lead to new diagnostics or new therapeutic approaches, especially for ALS.” This new mechanism, or specific enzyme, can “tag” certain types of proteins to send them to join clumps. These clumps protect against neurodegenerative disease such as ALS, or Lou Gehrig’s disease. These findings provide a new perspective on the role of protein clumps that have previously been associated with some types of neurological disease. Click here to read more. 


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