AANS Neurosurgeon | Volume 26, Number 1, 2017

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Neurodevelopmental Model of Williams Syndrome Offers Insight into Human Social Brain

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In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at the University of California San Diego, with colleagues at the Salk Institute for Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain. Scientists investigated Williams syndrome (WS), a rare genetic condition caused by deletion of one copy of 25 contiguous genes on chromosome 7, out of an estimated 30,000 genes in the brain. WS affects one in 10,000 people worldwide and an estimated 20,000 Americans. The conditions occurs equally in both genders and across cultures. To read more, click here.

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