AANS Neurosurgeon | Volume 27, Number 2, 2018


Glutamate Levels in the Brain May be Linked to Alcohol Craving

Craving consists of cognitive, emotional and behavioral elements related to a desire to drink alcohol and can be experienced during intoxication, withdrawal and/or prior relapse. Different types of craving are hypothesized to be associated with different neurotransmitter systems. For example, reward craving may be mediated by dopamine and opioids, obsessive craving by serotonin and relief craving by glutamate. This study used magnetic resonance of spectroscopy (1H-MRS) to examine the correclation between craving and glutamate levels in the left dorsolateral prefrontal cortex (LDLPFC) of patients with alcohol disorders. To read more, click here.

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