Drug Improves Brain Performance in Rett Syndrome Mice
After learning that a small-molecule drug improves breathing in a mouse model of the neurodevelopmental disorder Rett syndrome, University of Alabama at Birmingham researcher Lucas Pozzo-Miller, Ph.D., wondered if he could test it on other brain functions.
Pozzo-Miller has now found that the brain penetrant drug — a small-molecule mimetic of BDNF, or brain derived neurotrophic factor — is able to improve brain performance in Rett syndrome mice — specifically synaptic plasticity in the hippocampus and object location memory. The hippocampus is involved in learning and memory.
Click here to read more.
Chicago Review Course in Neurological Surgery
Jan. 24-Feb. 3, 2019; Chicago
Richard Lende Winter Neurosurgery Conference
Feb. 1-5, 2019; Snowbird, Utah
2019 NASBS Annual Meeting
Feb. 15-17, 2019; Orlando, Fla.
12th Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery
Feb. 22-24, 2019; Lake Buena Vista, Fla.