NUS Researchers Identify Potential Target for Treatment of Aggressive Brain Cancer
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have discovered that the BCL6 protein could potentially be used as a marker to predict clinical outcomes of patients suffering from Glioblastoma Multiforme (GBM), the most malignant cancer of the brain. Specifically, the study, led by Professor H. Phillip Koeffler, senior principal investigator at CSI Singapore, found that GBM patients with lower levels of the BCL6 protein have a higher survival rate than those with high BCL6 expression. The study also suggests BCL6 as a possible target for GBM treatment – controlling the levels and activities of the BCL6 protein could potentially contribute to treatment of the disease. GBM is aggressively cancerous as the cells reproduce rapidly and spread extensively in the brain and is also highly resistant to conventional therapy. This makes treatment exceptionally tough and challenging. GBM patients usually survive less than 15 months after diagnosis.
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14th International Conference on Neurology, Neuroscience and Neuromuscular Disorders
June 17-18, 2019; Tokyo
CARS 2019 Computer Assisted Radiology and Surgery
June 18-21, 2019; Rennes, France
18th Meeting of WSSFN
June 24-27, 2019; New York
International Summer School Transnasal Endoscopic Surgery: From Sinuses to Skull Base
June 24-28, 2019; Brescia, Italy
The Society of University Neurosurgeons Annual Meeting
June 26-30, 2019; Dubrovnik, Croatia