“Glioblastomas are aggressive and tenacious in patients, but have always been very difficult to keep alive in the lab,” said UC San Francisco postdoctoral researcher Aparna Bhaduri, PhD. “In previous attempts to study glioblastomas in mice, only 5 to 10 percent of human tumors survive transplantation into the animals, making us suspect that these tumors may differ in important ways from the ones that don’t survive.”