You are viewing AANS Neurosurgeon Volume 28, Number 2, 2019. View our current issue, Volume 29, Number 2, 2020

AANS Neurosurgeon | Volume 28, Number 2, 2019


Brain-Gut Communication in Worms Demonstrates How Organs Can Work Together to Regulate Lifespan

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Cells and tissues continuously use information from our environments—and from each other—to actively coordinate the aging process. A new study from the University of Michigan Life Sciences Institute now reveals how some of that cross-talk between tissues occurs in a common model organism.

Recent research has shown that signaling between the intestine and brain can regulate a range of biological processes. So far, research has focused mainly on how signals from the gut can affect neurological functions,including some neurodegenerative diseases. Much less is known about how the brain communicates with the gut to affect certain biological process, such as aging.

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