UCLA researchers have found that mental sharpness in women begins to decline as early as their 50s. The study, which followed the same group of healthy women for 10 years after menopause, found that their average decline in mental processing ability was 5 percent during the decade-long period. Cognitive processing speed, which includes speed of perception and reaction, showed an average decline of around 1 percent every two years and verbal memory declined on average around 1 percent every five years. Previous longitudinal studies in midlife women had failed to consistently detect these cognitive declines. For this study, the researchers accounted for what are called “practice effects,” which is when repeat testing using the same tests in the same individuals influence the results. Practice effects mask some effects of the menopause transition. In this way they were able to uncover evidence of declines in two domains of cognitive functioning — processing speed and verbal memory.

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