AANS Neurosurgeon | Volume 26, Number 1, 2017


What Turns Benign Central Nervous System Tumors Deadly

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More than one in three tumors that affect the central nervous system are meningiomas and most are benign. However, some can turn deadly. In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40 percent chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors. The new genetic analysis has identified molecular mechanisms involved in the formation of primary atypical meningiomas. “The tumor cells behave more like stem cells. They are less specialized and divide rapidly,” said Yale’s Akdes Serin Harmanci, the first author of the paper.

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Microsurgery Course Zurich
March 29-April 1, 2017; Zurich, Switzerland

12th World Congress on Brain Injury
March 29-April 1, 2017; New Orleans

2017 National Neuroscience Review
March 31-April 1, 2017; National Harbor, Md.

Brain & Brain PET 2017
April 1-4, 2017; Berlin, Germany

Neurosurgical Society of America Annual Meeting 2017
April 2-5, 2017; Jacksonville, Fla.

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