AANS Neurosurgeon | Volume 26, Number 4, 2017


What Turns Benign Central Nervous System Tumors Deadly

More than one in three tumors that affect the central nervous system are meningiomas and most are benign. However, some can turn deadly. In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40 percent chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors. The new genetic analysis has identified molecular mechanisms involved in the formation of primary atypical meningiomas. “The tumor cells behave more like stem cells. They are less specialized and divide rapidly,” said Yale’s Akdes Serin Harmanci, the first author of the paper.

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Winter Clinics for Cranial and Spinal Surgery
Feb. 25, 2018 - Mar. 1, 2018; Snowmass Village, Colo.

69th Southern Neurosurgical Society Annual Meeting
Feb. 28, 2018 - Mar. 3, 2018; San Juan, PR

Second International Brain Mapping Course
April 26-27, 2018; New Orleans

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