AANS Neurosurgeon | Volume 27, Number 2, 2018


Transplantation of Unique, Newly Discovered Stem Cells May Lead to Promising Stroke Therapy

Restoring hopes that stem cell transplantation can aid in stroke recovery despite cellular irregularities, new evidence has surfaced that a new type of cell may be used to reduce the overall risks and complications. A joint team of Japanese and American researchers reported in the journal Stem Cells that multi-lineage-differentiating stress-enduring (Muse) cells are “unique stem cells that are able to self-renew and also display high efficiency for differentiating into neuron-like cells.” The researchers also explained that, unlike mesenchymal stem cells (MSCs) that have previously been used in stem cell transplantation in stroke-related clinical trials, in the present study, Muse cells were found to possess functional characteristics of neurons as they attain the attributes of the host microenvironment. “When Muse cells were transplanted into to the brains of rats modeled with stroke, they attained neuronal characteristics,” said the study’s lead researcher. To learn more about this study, click here.

Comments are closed.