AANS Neurosurgeon | Volume 26, Number 4, 2017

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Study: New Approach to Destroying Deadly Brain Tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center. The research demonstrates in mice that a combination of medications – traditionally used separately to treat lung cancer and arthritis – can destroy glioblastoma, a difficult-to-treat brain tumor that is lethal to most patients in little more than a year. The combination of these medications disables two proteins responsible for helping the cancer cells survive, providing a therapy that UT Southwestern is working to fast-track for clinical use. “This could be a groundbreaking treatment. If it works in patients, then it will be an important advance,” said Dr. Amyn Habib, a member of UT Southwestern’s Peter O’Donnell Jr. Brain Institute and the Harold C. Simmons Comprehensive Cancer Center. The research answers a decades-old question of why a treatment that disables a protein common in various cancers has been effective in some forms of lung and colon cancer but not in glioblastoma.

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Calendar/Courses

Winter Clinics for Cranial and Spinal Surgery
Feb. 25, 2018 - Mar. 1, 2018; Snowmass Village, Colo.

69th Southern Neurosurgical Society Annual Meeting
Feb. 28, 2018 - Mar. 3, 2018; San Juan, PR

Second International Brain Mapping Course
April 26-27, 2018; New Orleans

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