AANS Neurosurgeon | Volume 27, Number 2, 2018


Study Finds Only a Small Portion of Synapses May Be Active During Neurotransimission

Scientists from Columbia University have been studying how information is transmitted in the brains of mice using a new optical technique. They found that only a small portion of synapses were active at any given time. “Understanding how we accomplish complex tasks, such as learning and memory, requires us to look at how our brains transmit key signals – called neurotransmitters – across synapses from one neuron to another,” said David Sulzer, PhD, professor of neurobiology in Psychiatry, Neurology and Pharmacology at Columbia University Medical Center (CUMC). “Older techniques only reveale what was going on in large groups of synapses. We needed a way to observe the neurotransmitter activity of individual synapses, to help us better understand their intricate behavior.” To read more, click here

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