AANS Neurosurgeon | Volume 26, Number 3, 2017

Advertisement

Scientists Use New Data Mining Strategy to Spot Those at High Alzheimer’s Risk

Method could group similar Alzheimer’s patients for more precise drug trials

 

The push to develop treatments for Alzheimer’s disease has been a promising and disappointing endeavor over the past two decades, yielding a greater understanding of the disease yet still failing to generate successful new drugs.

To blame are the many undefined subtypes of mild cognitive impairment, a precursor to Alzheimer’s disease.

“Everyone thinks Alzheimer’s is one disease, but it’s not,” said P. Murali Doraiswamy, M.D., professor of psychiatry and director of the neurocognitive disorders program at Duke Health. “There are many subgroups. If you enroll all different types of people in a trial, but your drug is targeting only one biological pathway, of course the people who don’t have that abnormality are not going to respond to the drug, and the trial is going to fail.”

Click here to read more.

Calendar/Courses

8th World Congress of Neuroendoscopy
Nov. 1-4, 2017; Cape Town, South Africa

3rd Annual Selected Topics in Craniomaxillofacial Surgery
Nov. 4, 2017 - Nov. 5, 2017; Boston, Mass.

Interactive Calendar

Leave a Reply

Be the first to reply using the above form.