AANS Neurosurgeon | Volume 27, Number 2, 2018

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Researchers Uncover Culprit in Parkinson's Brain Cell Die-Off

An estimated 10 million people worldwide are living with Parkinson’s disease—an incurable neurodegenerative disorder that leads to an increasing loss of motor control. 

If we could peer into the brains of these patients, we’d see two hallmarks of the disease. First, we’d see a die-off of the brain cells that produce a chemical called dopamine. We’d also see protein clumps called Lewy bodies inside the neurons.

Corinne Lasmézas, DVM, PhD, a professor on the Florida campus of The Scripps Research Institute (TSRI), believes a key to treating Parkinson’s is to study possible links between these two phenomena.

Now her group has discovered a connection between neuronal death and Lewy bodies.

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