Researchers Identify Molecular Target for Brain Cancer, Develop Immunotherapy Approach to Attack It
An international team of researchers has genetically engineered cancer-killing immune cells that can hunt brain tumors displaying a new molecular target that is highly prevalent on brain cancer cells. Based on the findings from their early, preclinical studies, the researchers believe their approach holds promise for a new immunotherapy treatment for glioblastoma, which is the most lethal primary brain tumor.
Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center, in collaboration with the Fondazione Istituto di Ricerca e Cura a Carattere Scientifico in Milan, Italy, report they modified immune cells to hunt brain tumors displaying a new molecular target called CSPG4, which they determined is highly prevalent on brain cancer cells. Their preclinical studies of immune cells engineered to recognize CSPG4 showed promise for controlling tumor growth in mouse and cell models for glioblastoma.
Click here to read more.
Chicago Review Course in Neurological Surgery
Jan. 24-Feb. 3, 2019; Chicago
Richard Lende Winter Neurosurgery Conference
Feb. 1-5, 2019; Snowbird, Utah
2019 NASBS Annual Meeting
Feb. 15-17, 2019; Orlando, Fla.
12th Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery
Feb. 22-24, 2019; Lake Buena Vista, Fla.