You are viewing AANS Neurosurgeon Volume 26, Number 4, 2017. View our current issue, Volume 27, Number 3, 2018

AANS Neurosurgeon | Volume 26, Number 4, 2017

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Researchers Discover That a Blood Thinner Significantly Reduces the Risk of Death After Non-Cardiac Surgery

First randomized controlled trial to evaluate a treatment for MINS

 

Researchers in Hamilton have discovered that a blood-thinning drug, dabigatran, significantly reduces the risk of death, heart attack, stroke, and other heart or blood-vessel complications in patients who have a heart injury following major, non-cardiac surgery.

Every year, approximately eight million people world-wide develop a condition called myocardial injury after non-cardiac surgery (MINS), which refers to damage incurred to the tissue of the heart in response to the stress of surgery on the body. The condition affects patients undergoing major procedures such as a hip or knee replacement, bowel resection, or abdominal aortic aneurysm repair, and can lead to severe complications including heart attack, stroke, blood clots, amputations, and death.

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