AANS Neurosurgeon | Volume 26, Number 1, 2017

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Research Hints at Underlying Cause for Alzheimer's Drug Trial Failures

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Because Alzheimer’s disease (AD) is the leading cause of dementia, many people use the two terms interchangeably. But inadequate blood flow to the brain due to micro infarcts, mini-strokes or strokes is hallmark of a disease called Vascular Cognitive Impairment and Dementia (VCID). VCID is the second most common cause of dementia, and the two are not mutually exclusive – researchers estimate that 40-60 percent of Alzheimer’s disease patients also have VCID.

A paper recently published in the Journal of Neuroscience by Donna Wilcock, PhD, of the UK Sanders-Brown Center on Aging, reports that a certain form of immunotherapy targeted to Alzheimer’s patients may be ineffective when that patient also has VCID.

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Calendar/Courses

2017 National Neuroscience Review
March 31-April 1, 2017; National Harbor, Md.

Brain & Brain PET 2017
April 1-4, 2017; Berlin, Germany

Neurosurgical Society of America Annual Meeting 2017
April 2-5, 2017; Jacksonville, Fla.

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