AANS Neurosurgeon | Volume 26, Number 4, 2017


New Technique Generates Human Neural Stem Cells for Tissue Engineering, 3-D Brain Models

Tufts University researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain. The work could pave the way for experiments that engineer other innervated tissues, such as the skin and cornea, and for the development of human brain models with diseases such as Alzheimer’s or Parkinson’s. Researchers converted human fibroblasts and adipose-derived stem cells into stable, human induced neural stem cell (hiNSC) lines that acquire the features of active neurons within as few as four days, compared to the typical weeks, according to the paper. To read more, click here.

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