New radiotherapy treatment for brain cancer offers superior preservation of cognitive function, Mayo researchers say
When it comes to radiation therapy to treat brain cancer, hippocampal-avoidance whole-brain radiotherapy in conjunction with the drug memantine better preserved patients’ cognitive function and demonstrated similar cancer control outcomes, compared to traditional whole-brain radiotherapy with memantine.
“The hippocampus is a part of the brain associated with the limbic system and cognitive functions including memory,” says says Paul Brown, M.D., a radiation oncologist at Mayo Clinic and senior author of the study. “Based on decades of translational studies, we know that even relatively modest doses of radiation to the hippocampi region of the brain contributes to cognitive problems for patients, such as memory loss.” Dr. Brown says hippocampal-avoidance whole-brain radiotherapy was developed to help patients with brain cancer avoid cognitive damage during whole-brain radiation therapy.
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Chicago Review Course in Neurological Surgery
Jan. 24-Feb. 3, 2019; Chicago
Richard Lende Winter Neurosurgery Conference
Feb. 1-5, 2019; Snowbird, Utah
2019 NASBS Annual Meeting
Feb. 15-17, 2019; Orlando, Fla.
12th Annual International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery
Feb. 22-24, 2019; Lake Buena Vista, Fla.
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