AANS Neurosurgeon | Volume 27, Number 2, 2018


New Clues About the Aging Brain's Memory Functions

In this study, researchers found that the dopamine D2 receptor is linked to long-term, episodic memory. The function of this receptor often reduces with age and the onset of dementia in certain patients. It was identified that the D2 receptor was positively linked to episodic memory, but not to working memory. It also affects how the hippocampus functions. “Our results link the dopamine D2 receptor to long-term episodic memory, likely via hippocampus functioning. Episodic memory is often reduced with age and in people with dementia. Hence, impairment of the dopamine system is important to consider when attempting to understand the bases of impaired cognitive abilities due to aging,” says Lars Nyberg, professor in Neuroscience and director at Umea Centre for Functional Brain Imaging (UFBI). To read more, click here.

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