Neuroscientists Focus on Cell Mechanism That Promotes Chronic Pain
Researchers have discovered a new pain-signaling pathway in nerve cells that eventually could make a good target for new drugs to fight chronic pain.
The findings, published by a UT Dallas neuroscientist and his colleagues, suggest that inhibiting a process called phosphorylation occurring outside of nerve cells might disrupt pain signals, and provide an alternative to opioid drugs for alleviating chronic pain.
Dr. Ted Price, the study’s co-author and associate professor of neuroscience in the School of Behavioral and Brain Sciences at UT Dallas, said the finding is significant.
“We found a key new signaling pathway that can be managed,” Price said. “Now we hope we can use the findings to discover a new drug.”
Phosphorylation is a biological process that occurs when a kinase — a type of enzyme — attaches a chemical called phosphate to a protein. This common process modifies proteins and their functions.
Click here to read more.
Intraoperative Neurophysiology in Neurosurgery: The Essentials. 2nd Edition
Dec. 14-16, 2017; Verona, Italy
Mayo Clinic Neuroscience and Oncology Innovation Summit 2017
Dec. 14, 2017 - Dec. 16, 2017; Orlando, Fla.
43rd Annual Meeting of Louisiana Neurosurgical Society
Jan. 12, 2018 - Jan. 13, 2018; Shreveport, La.
2018 CANS Annual Meeting
Jan. 12-14, 2018; San Diego
Be the first to reply using the above form.