AANS Neurosurgeon | Volume 26, Number 3, 2017

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Enzyme Hyaluronidase Shows Promised as Treatment for Muscle Stiffness Caused by Brain Injury

A naturally occurring enzyme called hyaluronidase may be an effective alternative treatment for spasticity, or muscle stiffness, a disabling condition in people who have had a stroke or other brain injury.

That is the finding of a study from NYU Langone Medical Center published in the July print issue of EBioMedicine, with a corresponding commentary on the study published in the same issue.

The study found that injections of hyaluronidase reduced muscle stiffness in patients with neurological injury without causing muscle weakness like conventional treatments such as botulinum toxin.

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