AANS Neurosurgeon | Volume 27, Number 2, 2018


Are Drops in Estrogen Levels More Rapid in Women with Migraine?

It has been long known that sex hormones, such as estrogen, play a role in migraines for women. However, how the hormone level actually affects the migraine is still a mystery. In a recent study, researchers were able to discover that estrogen levels may drop more rapidly in the days just before mestruation than they do for women who do not have a history of migraines. Other hormone patterns displayed no differences when comparing women with a history of migraines and women who do not. “These results suggest that a ‘two-hit’ process may link estrogen withdrawal to menstrual migraine. More rapid estrogen decline may make women vulnerable to common triggers for migraine attacks such as stress, lack of sleep, foods and wine,” said study author Jelena Pavlovic, MD, PhD, of Albert Einstein College of Medicine/Montefiore Medical Center in Bronx, N.Y., and a member of the American Academy of Neurology. To read more, click here.

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