AANS Neurosurgeon | Volume 27, Number 3, 2018

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DBS Treatment May Slow the Progression of Parkinson’s Tremor in Early-Stage Patients

Deep brain stimulation (DBS) may slow the progression of tremor for early-stage Parkinson’s disease patients, according to a Vanderbilt University Medical Center study.

The study is the first evidence of a treatment that slows the progression of one of the cardinal features of Parkinson’s, but a larger-scale clinical trial across multiple investigational centers is needed to confirm the finding.

“The finding concerning tremor progression is truly exceptional,” said senior author David Charles, MD, professor and vice-chairman of Neurology. “It suggests that DBS applied in early-stage Parkinson’s disease may slow the progression of tremor, which is remarkable because there are no treatments for Parkinson’s that have been proven to slow the progression of any element of the disease.”

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