Connection Found Between Memory Mechanisms and Resistance to Epilepsy

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A new study undertaken jointly by researchers from the Sagol Department of Neurobiology at the University of Haifa and European researchers exposes a new biological mechanism that, on the one hand, damages a very specific type of memory, but at the same time provides resistance to epilepsy. Research student Elham Taha from the laboratory of Prof. Kobi Rosenblum, who undertook the research, explains, “In both healthy and sick brains, the relationship between the activities of the nerve cells that cause the transfer of information and activities delaying the transmission of information is extremely important. We know that damage to this relationship forms the basis of various brain diseases, such as neuro-developmental diseases and epilepsy. The aim of our study was to isolate molecular components that serve the creation of long-term memories. We were surprised to find the molecular change we created led to a minor change in this relationship in the hippocampus, but also created resistance to epileptic seizures. Thus the finding creates new possibilities for developing drugs for the treatment of epilepsy.” 

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