AANS Neurosurgeon | Volume 26, Number 1, 2017

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A Common Nerve Protein Elevated in Aggressive Neuroblastomas

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A protein produced by nerve cells appear to be elevated in the blood of those with an aggressive form of neuroblastoma. The finding could potentially lead to a prognostic test for the disease or be used to monitor its progress. Neuroblastoma is a pediatric cancer with varying types, ranging from spontaneously regressing to untreatable fatal tumors. Consequently, treatment strategies vary significantly between patients, encompassing different approaches including observation alone or intensive chemo-and radiotherapy. “Given the severe late effects of anti-cancer treatment administered to infants and children, proper disease stratification is of utmost importance for neuroblastoma patients,” explains Joanna Kitlinska, PhD, associate professor in the department of biochemistry and molecular and cellular biology at Georgetown University Medical Center. Click here to read more.

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