Case Western Reserve University School of Medicine Scientists Develop Therapeutic Protein, Protect Nerve Cells from Huntington’s Disease

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Findings offer new approach to prevent disease symptoms

A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington’s disease. Huntington’s disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein which can impair energy-producing parts of the nerve cells called mitochondria. The mutant protein destroy nerve cells and slowly chips away at a person’s ability to walk, speak and control their behavior. Xin Qi, PhD, assistant professor of physiology and biophysics at Case Western Reserve University School of Medicine has been looking for proteins that interact with mutant huntingtin to better understand the initial steps of Huntington’s disease progression. To read more, click here.

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