AANS Neurosurgeon | Volume 26, Number 3, 2017

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‘Brain Glue’ Repairs Traumatic Brain Injuries

Hydrogel mimics the composition and mechanics of the brain

 

Researchers at the University of Georgia’s Regenerative Bioscience Center have developed Brain Glue, a substance that could one day serve as a treatment for traumatic brain injuries, or TBIs.

The Brain Glue is a hydrogel matrix with a gelatin-like consistency that acts as a scaffolding for transplanted stem cells, which are capable of repairing damaged tissue. With the unique ability to take the shape of the void left in the brain after a severe trauma, the Brain Glue will enable a more natural healing environment for stem cells to colonize and regenerate.

Lohitash Karumbaiah, assistant professor in UGA’s College of Agricultural and Environmental Sciences, led the team that designed and created Brain Glue. The main difference between Brain Glue and other synthetic hydrogels, according to the team, is the variety of possibilities to trap neural stem cells, improve integration and reduce the likelihood of rejection.

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